Emma Wood

Techniques

Lab Members
Tizzy Allison (PhD student)
Antonis Asiminas (PhD student)
Bryan Jenkins (MSc student)

 

Dr. Emma R. Wood
Senior Lecturer
Tel: +44(0) 131 650 3531

 

Lab Webpage

E-mail: Emma.Wood@ed.ac.uk

Research Interests
The primary focus of the Memory and Space Laboratory (run jointly with Dr Paul Dudchenko) is on the neural basis of learning, memory and spatial cognition, with a particular emphasis on the role of the hippocampus and its interactions with up- and downstream structures, including the lateral and medial entorhinal cortices and the postsubiculum (dorsal presubiculum). We use an integrated approach combining behavioural analysis in rodents with in vivo single unit recording, and various lesion, pharmacological and genetic techniques to address these issues.

Research collaborations at the University of Edinburgh include:

    • With Peter Kind, Richard Morris and members of the Patrick Wild Centre, developing rat models of neurodevelopmental disorders for translational research.
    • With Megan Holmes and Jeremy Hall, investigating the effects of early life events on cognition.
    • With Karen Horsburgh and colleagues, investigating the influence of vascular dysfunction on cognitive decline.

Key Publications
Bett D, Stevenson CH, Shires KL, Smith MT, Martin SJ, Dudchenko PA and Wood ER.  (2013) The postsubiculum and spatial learning: the role of postsubicular synaptic activity and synaptic plasticity in hippocampal place cell-, object- and object-location memory. J Neuroscience 33(16): 6928-6943.
Bett D, Wood ER, and Dudchenko PA. (2012) The postsubiculum is necessary for spatial alternation but not for homing by path integration. Behavioral Neuroscience. 126(2):237-48. doi: 10.1037/a0027163.
Bett D, Allison E, Murdoch LH, Kaefer K, Wood ER and Dudchenko PA. (2012) The neural substrates of deliberative decision making: contrasting effects of hippocampus lesions on performance and vicarious trial-and-error behavior in a spatial memory task and a visual discrimination task. Frontiers in Behavioural Neuroscience 30 October 2012. doi: 10.3389/fnbeh.2012.00070.
Langston, RF and Wood, ER. (2010) Associative recognition and the hippocampus: differential effects of hippocampal lesions on object-place, object-context and object-place-context memory. Hippocampus 20(10) 1139-53. doi: 10.1002/hipo.20714.
Langston RF, Stevenson CH, Wilson CL, Saunders I and Wood ER. (2010) The role of hippocampal subregions in memory for stimulus associations Behavioural Brain Research 215: 275-291. doi:10.1016/j.bbr.2010.07.006.

Funding Sources
Human Frontiers Science Programme (HFSP), BBSRC, Patrick Wild Centre

Biography
You can access a short biography by clicking here.