Dr. Santiago Canals
Group Leader, Consejo Superior de Investigaciones Científicas (CSIC)
Neuroscience Institute (CSIC-UMH), San Juan de Alicante, Spain
Tel: +34 965 919202





E-mail: scanals@umh.es

Research Interests
Plasticity of Brain Networks
We are interested in understanding how memories are encoded, stored and retrieved in our brains. We investigate how modifications in synaptic activity, as those occurring during everyday-life experience or those related to drug consumption habits, shape the functional structure of the brain, recruiting relevant networks in particular contexts and govern the behavioural output. In doing so, we study the mechanism governing information routing in the complex network of parallel and highly distributed connections implemented in the brain. To this end we use animal models and combine functional magnetic resonance imaging (fMRI), electrophysiological recordings and behavioural testing.

Key Publications
Alvarez-Salvado E, Pallarés V, Moreno A and Canals S. (2013) Functional MRI of long-term potentiation: imaging network plasticity. Philos Trans R Soc Lond B Biol Sci.. 369(1633):20130152. doi: 10.1098/rstb.2013.0152.
Moreno A, Jego P, de la Cruz F and Canals S. (2013) Neurophysiological, metabolic and cellular compartments that drive neurovascular coupling and neuroimaging signals. Front Neuroenergetics. 5:3. doi: 10.3389/fnene.2013.00003.eCollection9
Canals S, Beyerlein M, Merkle H and Logothetis NK. (2009) Functional MRI evidence for LTP-induced neural network reorganization. Curr Biol. 19(5):398-403. doi: 10.1016/j.cub.2009.01.037.
Canals S, Beyerlein M, Keller AL, Murayama Y and Logothetis NK. (2008) Magnetic resonance imaging of cortical connectivity in vivo. Neuroimage. 40(2):458-72. doi: 10.1016/j.neuroimage.2007.12.007.